PubMed COVID-19 Clinical Care
22101 - 22110 of 44979 results found
Mitochondrial mass of circulating NK cells as a novel biomarker in severe SARS-CoV-2 infection
Description
CONCLUSION: NK-MM was not only associated with disease severity, its abnormal increases or decreases also predicted mortality risk. The resulting decision tree prediction model is the first to focus on immune monitoring indicators to provide decision
Impact of COVID-19 on pediatric emergency fellowship training in Saudi Arabia
Description
CONCLUSION: The COVID-19 pandemic had significant effects on clinical procedures and academic activities in the PEM fellowship program. The impact was consistently perceived across PEM program directors and fellows. Technology-driven solutions are
Comparative analysis of CRP as a biomarker of the inflammatory response intensity among common viral infections affecting the lungs: COVID-19 versus influenza A, influenza B and respiratory syncytial virus
Description
Severe acute respiratory syndrome-corona virus 2 (SARS-CoV-2) is associated with significant morbidity and mortality. C-reactive protein (CRP) is a useful inflammatory biomarker for patients admitted with an infection. This study aimed to compare CRP
SARS-CoV-2 spike protein induces endothelial inflammation via ACE2 independently of viral replication
Description
COVID-19, caused by SARS-CoV-2, is a respiratory disease associated with inflammation and endotheliitis. Mechanisms underling inflammatory processes are unclear, but angiotensin converting enzyme 2 (ACE2), the receptor which binds the spike protein
The immunogenicity of Alum+CpG adjuvant SARS-CoV-2 inactivated vaccine in mice
Description
The ongoing evolution and emergence of SARS-CoV-2 variants have raised concerns regarding the efficacy of existing vaccines and therapeutic agents. This study aimed to investigate the immunogenicity of an aluminum hydroxide (Alum) and CpG adjuvanted
In silico epitope prediction and evolutionary analysis reveals capsid mutation patterns for enterovirus B
Description
Enterovirus B (EVB) is a common species of enterovirus, mainly consisting of Echovirus (Echo) and Coxsackievirus B (CVB). The population is generally susceptible to EVB, especially among children. Since the 21st century, EVB has been widely prevalent
Autumn in New York: The case of long-term care facilities in the "Safe Staffing" lawsuit with less staffing but similar COVID-19 outcomes
Description
BACKGROUND AND OBJECTIVES: In 2022, 239 New York state Long-Term Care Facilities (LTCFs) challenged a "Safe Staffing" law in court. Our study compares LTCFs involved and not involved in the lawsuit, testing for differences in staffing measures and
Association between COVID-19 and myasthenia gravis (MG): A genetic correlation and Mendelian randomization study
Description
CONCLUSION: Our study did not find evidence of a genetic correlation or causal relationship among COVID-19 susceptibility, hospitalization, severity, and MG. Future studies with more GWAS data are needed to evaluate the association between COVID-19